Clinical efficacy of low-level laser therapy on localized canine atopic dermatitis severity score and localized pruritic visual analog score in pedal pruritus due to canine atopic dermatitis

Vet Dermatol. 2014 Oct;25(5):464-e74. doi: 10.1111/vde.12144. Epub 2014 Jun 9.

Abstract

Background: Canine atopic dermatitis is a genetically predisposed inflammatory skin disease often requiring multimodal treatment. There is a need to find further low-risk adjunctive therapies.

Hypothesis/objectives: To evaluate the localized effect of low-level laser therapy (LLLT) on the paws of dogs with atopic dermatitis using a localized canine atopic dermatitis severity score (LCADSS) and owner localized pruritic visual analog score (LPVAS) in comparison to treatment with a placebo.

Animals: Thirty client-owned dogs with symmetrical pedal pruritus due to canine atopic dermatitis.

Methods: Dogs were randomly assigned into two groups. In each group, one paw was treated with LLLT and one paw treated with a placebo laser (comparing either both fore- or hindpaws). Treatments were administered at 4 J/cm(2) (area from carpus/tarsus to distal aspect of digit 3) three times per week for the first 2 weeks and two times per week for the second 2 weeks. Scores were assessed for each paw at weeks 0, 2, 4 and 5.

Results: There were no significant differences in LCADSS or LPVAS between LLLT and placebo treatments between weeks 0 and 5 (P = 0.0856 and 0.5017, respectively). However, LCADSS and LPVAS significantly decreased from week 0 at weeks 2, 4 and 5 in both LLLT and placebo groups (P < 0.0001 for all).

Conclusions and clinical importance: Low-level laser therapy is not an effective localized treatment for pedal pruritus in canine atopic dermatitis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Dermatitis, Atopic / complications
  • Dermatitis, Atopic / radiotherapy
  • Dermatitis, Atopic / veterinary*
  • Dog Diseases / diagnosis
  • Dog Diseases / radiotherapy*
  • Dogs
  • Female
  • Foot Dermatoses / radiotherapy
  • Foot Dermatoses / veterinary*
  • Low-Level Light Therapy / methods
  • Low-Level Light Therapy / veterinary*
  • Male
  • Pruritus / diagnosis
  • Pruritus / etiology
  • Pruritus / veterinary*
  • Severity of Illness Index
  • Treatment Outcome
  • Visual Analog Scale