Dietary and lifestyle guidelines for the prevention of Alzheimer's disease

Neurobiol Aging. 2014 Sep:35 Suppl 2:S74-8. doi: 10.1016/j.neurobiolaging.2014.03.033. Epub 2014 May 14.


Risk of developing Alzheimer's disease is increased by older age, genetic factors, and several medical risk factors. Studies have also suggested that dietary and lifestyle factors may influence risk, raising the possibility that preventive strategies may be effective. This body of research is incomplete. However, because the most scientifically supported lifestyle factors for Alzheimer's disease are known factors for cardiovascular diseases and diabetes, it is reasonable to provide preliminary guidance to help individuals who wish to reduce their risk. At the International Conference on Nutrition and the Brain, Washington, DC, July 19-20, 2013, speakers were asked to comment on possible guidelines for Alzheimer's disease prevention, with an aim of developing a set of practical, albeit preliminary, steps to be recommended to members of the public. From this discussion, 7 guidelines emerged related to healthful diet and exercise habits.

Keywords: Alzheimer's disease; Copper; Dementia; Exercise; Iron; Nutrition; Prevention; Saturated fat; Trans fatty acids; Vitamin E.

Publication types

  • Review

MeSH terms

  • Alzheimer Disease / prevention & control*
  • Diet, Vegetarian
  • Exercise / physiology
  • Fatty Acids / adverse effects
  • Humans
  • Life Style*
  • Nutrition Policy*
  • Risk
  • Trans Fatty Acids / adverse effects
  • Vitamin B 12 / administration & dosage
  • Vitamin E


  • Fatty Acids
  • Trans Fatty Acids
  • Vitamin E
  • Vitamin B 12