Significance of nutrition in pulmonary tuberculosis

Crit Rev Food Sci Nutr. 2015;55(7):955-63. doi: 10.1080/10408398.2012.679500.


Malnutrition and tuberculosis are both problems mostly of the developing countries. Tuberculosis can lead to malnutrition and malnutrition may predispose to tuberculosis. Poor nutrition leads to protein-energy malnutrition and micronutrients deficiencies which lead to immunodeficiency. This secondary immunodeficiency increases the host's susceptibility to infection and hence increase the risk for developing tuberculosis. Tuberculosis itself leads to reduction in appetite, nutrient malabsorption, micronutrient malabsorption, and altered metabolism leading to wasting and poor nutritional status. Nutritional status and dietary intake and hence nutritional status of patients get improved during antituberculosis treatment.

Keywords: Tuberculosis; immunodeficiency; malnutrition; micronutrients.

Publication types

  • Review

MeSH terms

  • Antitubercular Agents / therapeutic use*
  • Appetite / drug effects
  • Developing Countries*
  • Eating / drug effects
  • Humans
  • Malnutrition / complications*
  • Micronutrients / pharmacology
  • Nutritional Status* / drug effects
  • Risk Factors
  • Treatment Outcome
  • Tuberculosis, Pulmonary / drug therapy*
  • Tuberculosis, Pulmonary / etiology
  • Tuberculosis, Pulmonary / physiopathology


  • Antitubercular Agents
  • Micronutrients