doi: 10.1210/endo-124-1-546.
Evidence for prostaglandins and leukotrienes as mediators of phase I of estrogen action in implantation in the mouse
Affiliations
- PMID: 2491811
- DOI: 10.1210/endo-124-1-546
Item in Clipboard
Evidence for prostaglandins and leukotrienes as mediators of phase I of estrogen action in implantation in the mouse
Endocrinology.
1989 Jan.
Abstract
The inhibition of the cyclooxygenase and/or the lipoxygenase pathways by indomethacin or nordihydroguaiaretic acid during Phase I of estrogen action interfered with estriol-induced initiation of implantation, but not uterine macromolecular uptake and water imbibition. This inhibition of implantation was completely reversed by supplementation with prostaglandin E2 or leukotriene C4. These results suggest that estrogen-induced initiation of implantation in a progesterone-primed uterus is mediated via prostaglandins and leukotrienes as components of Phase I of estrogen action.
Similar articles
-
Evidence for a possible role of prostaglandins in implantation in rats.Arch Int Pharmacodyn Ther. 1983 Apr;262(2):299-307. Arch Int Pharmacodyn Ther. 1983. PMID: 6409018
-
The lipoxygenase inhibitor, nordihydroguaiaretic acid, inhibits ovulation and reduces leukotriene and prostaglandin levels in the rat ovary.Biol Reprod. 1998 May;58(5):1211-6. doi: 10.1095/biolreprod58.5.1211. Biol Reprod. 1998. PMID: 9603255
-
Eicosanoid synthesis in murine macrophages can be shifted from prostaglandins to leukotrienes but not vice versa by specific inhibitors of cyclooxygenase or 5'-lipoxygenase activity.Adv Prostaglandin Thromboxane Leukot Res. 1991;21A:169-72. Adv Prostaglandin Thromboxane Leukot Res. 1991. PMID: 1825537 No abstract available.
-
Involvement of prostaglandins and leukotrienes in the pathogenesis of endotoxemia and sepsis.J Am Vet Med Assoc. 1992 Jun 15;200(12):1842-8. J Am Vet Med Assoc. 1992. PMID: 1639689 Review. No abstract available.
-
The role of leukotrienes and prostaglandins in asthma: evidence from clinical investigations.Adv Prostaglandin Thromboxane Leukot Res. 1990;20:209-16. Adv Prostaglandin Thromboxane Leukot Res. 1990. PMID: 2144694 Review. No abstract available.
Cited by
-
Montelukast induces beneficial behavioral outcomes and reduces inflammation in male and female rats.Front Immunol. 2022 Sep 6;13:981440. doi: 10.3389/fimmu.2022.981440. eCollection 2022. Front Immunol. 2022. PMID: 36148246 Free PMC article.
-
Glucose-6-phosphate isomerase is necessary for embryo implantation in the domestic ferret.Proc Natl Acad Sci U S A. 2003 Jul 8;100(14):8561-6. doi: 10.1073/pnas.1531024100. Epub 2003 Jun 25. Proc Natl Acad Sci U S A. 2003. PMID: 12826606 Free PMC article.
-
Changes in anandamide levels in mouse uterus are associated with uterine receptivity for embryo implantation.Proc Natl Acad Sci U S A. 1997 Apr 15;94(8):4188-92. doi: 10.1073/pnas.94.8.4188. Proc Natl Acad Sci U S A. 1997. PMID: 9108127 Free PMC article.
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources
Miscellaneous
