One-pot synthesis of benzo[4,5]imidazo[1,2-a]quinazoline derivatives via facile transition-metal-free tandem process

Shuai Fang; Xiaoyi Niu; Bingchuan Yang; Yanqiu Li; Xiaomeng Si; Lei Feng; Chen Ma

doi:10.1021/co500001u

One-pot synthesis of benzo[4,5]imidazo[1,2-a]quinazoline derivatives via facile transition-metal-free tandem process

ACS Comb Sci. 2014 Jul 14;16(7):328-32. doi: 10.1021/co500001u. Epub 2014 Jun 20.

Authors

Shuai Fang¹, Xiaoyi Niu, Bingchuan Yang, Yanqiu Li, Xiaomeng Si, Lei Feng, Chen Ma

Affiliation

¹ Key Laboratory of Special Functional Aggregated Materials, Ministry of Education, School of Chemistry and Chemical Engineering, Shandong University , Jinan, 250100, P. R. China.

PMID: 24919956
DOI: 10.1021/co500001u

Abstract

A one-pot transition metal-free method for synthesizing benzo[4,5]imidazo[1,2-a]quinazoline and imidazo[1,2-a]quinazoline derivatives has been developed. The approach is widely applicable to 2-fluoro-, 2-chloro-, 2-bromo- and 2-nitro-substituted aryl aldehyde and ketone substrates. The fluorescence properties of target compounds were studied.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Aldehydes / chemistry
Benzimidazoles / chemical synthesis*
Benzimidazoles / chemistry
Ketones / chemistry
Molecular Structure
Quinazolines / chemical synthesis*
Quinazolines / chemistry

Substances

Aldehydes
Benzimidazoles
Ketones
Quinazolines