Reference values and age and sex differences in physical performance measures for community-dwelling older Japanese: a pooled analysis of six cohort studies

PLoS One. 2014 Jun 12;9(6):e99487. doi: 10.1371/journal.pone.0099487. eCollection 2014.

Abstract

Objectives: To determine age- and sex-specific reference values for six physical performance measures, i.e. hand-grip strength, one-legged stance, and gait speed and step length at both usual and maximum paces, and to investigate age and sex differences in these measures among community-dwelling older Japanese adults.

Methods: We conducted a pooled analysis of data from six cohort studies collected between 2002 and 2011 as part of the Tokyo Metropolitan Institute of Gerontology-Longitudinal Interdisciplinary Study on Aging. The pooled analysis included cross-sectional data from 4683 nondisabled, community-dwelling adults aged 65 years or older (2168 men, 2515 women; mean age: 74.0 years in men and 73.9 years in women).

Results: Unweighted simple mean (standard deviation) hand-grip strength, one-legged stance, usual gait speed, usual gait step length, maximum gait speed, and maximum gait step length were 31.7 (6.7) kg, 39.3 (23.0) s, 1.29 (0.25) m/s, 67.7 (10.0) cm, 1.94 (0.38) m/s, and 82.3 (11.6) cm, respectively, in men and 20.4 (5.0) kg, 36.8 (23.4) s, 1.25 (0.27) m/s, 60.8 (10.0) cm, 1.73 (0.36) m/s, and 69.7 (10.8) cm, respectively, in women. All physical performance measures showed significant decreasing trends with advancing age in both sexes (all P<0.001 for trend). We also constructed age- and sex-specific appraisal standards according to quintiles. With increasing age, the sex difference in hand-grip strength decreased significantly (P<0.001 for age and sex interaction). In contrast, sex differences significantly increased in all other measures (all P<0.05 for interactions) except step length at maximum pace.

Conclusion: Our pooled analysis yielded inclusive age- and sex-specific reference values and appraisal standards for major physical performance measures in nondisabled, community-dwelling, older Japanese adults. The characteristics of age-related decline in physical performance measures differed between sexes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Age Distribution
  • Aged
  • Aged, 80 and over
  • Asian People*
  • Cohort Studies
  • Female
  • Humans
  • Japan
  • Linear Models
  • Male
  • Motor Activity / physiology*
  • Reference Values
  • Residence Characteristics*
  • Sex Characteristics*

Grants and funding

This study was supported by grants from the Tokyo Metropolitan Government, the Japan Arteriosclerosis Prevention Fund (jals.gr.jp/en/index.html), the Research Institute of Science and Technology for Society, the Japan Science and Technology Agency (www.ristex.jp/EN/index.html), International Life Sciences Institute of Japan (www.ilsijapan.org/English/ILSIJapan/ILJ/IL.php), Grants-in-Aid for Scientific Research (B) (2) 14370150, (B) 17390194, (B) 21390212, and a Grant-in-Aid for Exploratory Research 17659192 from the Japan Society for the Promotion of Science, and Health Labour Sciences Research Grants H14-Chouju-006, H15-Ganyobo-065, H15-Seisaku-017, H16-Chouju-031, H23-Chouju-Ippan-001, and H23-Chouju-Ippan-002 from the Ministry of Health, Labour and Welfare of Japan. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.