Identification of a Novel HIV-1 Circulating Recombinant Form (CRF72_BF1) in Deep Sequencing Data from Blood Donors in Southeastern Brazil

Rodrigo Pessôa; Anna Bárbara de Freitas Carneiro Proietti; Michael P Busch; Sabri S Sanabani

doi:10.1128/genomeA.00386-14

Identification of a Novel HIV-1 Circulating Recombinant Form (CRF72_BF1) in Deep Sequencing Data from Blood Donors in Southeastern Brazil

Genome Announc. 2014 Jun 12;2(3):e00386-14. doi: 10.1128/genomeA.00386-14.

Authors

Rodrigo Pessôa¹, Anna Bárbara de Freitas Carneiro Proietti², Michael P Busch³, Sabri S Sanabani⁴

Affiliations

¹ Department of Virology, São Paulo Institute of Tropical Medicine, University of São Paulo, São Paulo, Brazil.
² Foundation and Center for Hematology and Hemotherapy of Minas Gerais, Hemominas, Belo Horizonte, MG, Brazil.
³ Blood Systems Research Institute, San Francisco, California, USA.
⁴ Department of Pathology, LIM 03, Hospital das Clínicas, School of Medicine, University of São Paulo, São Paulo, Brazil sabyem_63@yahoo.com.

Abstract

We report the identification of a novel HIV-1 circulating recombinant form (CRF72_BF1) in deep sequencing data from peripheral blood mononuclear cells (PBMC) of five blood donors in southeastern Brazil. Detection of this circulating recombinant form (CRF) confirms the need for effective surveillance to monitor the prevalence and distribution of HIV variants in a variety of settings in Brazil.

Grants and funding

K24 HL075036/HL/NHLBI NIH HHS/United States