Acupuncture for treatment of secondary osteoporosis in patients with spinal cord injury: a controlled study

Acupunct Med. 2014 Oct;32(5):381-6. doi: 10.1136/acupmed-2013-010463. Epub 2014 Jun 12.

Abstract

Objective: We explored the effect of adjunctive acupuncture on secondary osteoporosis in patients with spinal cord injury (SCI).

Methods: Patients with subacute SCI were recruited and divided into two groups by patient choice: group 1 patients received standard combination therapy and group 2 patients received combination therapy plus acupuncture for 3 months. The concentrations of IgG, IgM and tumour necrosis factor α (TNFα) in serum and the bone mineral density were measured before and after treatment.

Result: The decrease in the concentration of TNFα and IgM in patients in group 2 compared with those in group 1 was statistically significant. The IgG level showed no significant change in either group. Bone mineral density increased more after adjunctive acupuncture, but the difference was not significant.

Conclusions: Further research is needed to determine whether acupuncture as an adjunct to combination therapy can reduce osteoporosis in patients with subacute SCI.

Trial registration number: P153-2008-36.

Keywords: CLINICAL PHYSIOLOGY; MOXIBUSTION; OSTEOPOROSIS ARTHRITIS.

Publication types

  • Controlled Clinical Trial

MeSH terms

  • Acupuncture Therapy*
  • Adult
  • Bone Density*
  • Combined Modality Therapy
  • Female
  • Humans
  • Immunoglobulin G / blood
  • Immunoglobulin M / blood*
  • Male
  • Middle Aged
  • Osteoporosis / blood
  • Osteoporosis / etiology
  • Osteoporosis / therapy*
  • Spinal Cord Injuries / complications*
  • Tumor Necrosis Factor-alpha / blood*

Substances

  • Immunoglobulin G
  • Immunoglobulin M
  • Tumor Necrosis Factor-alpha