Intravenous Immunoglobulin in the Treatment of Severe Clostridium Difficile Colitis

J Glob Infect Dis. 2014 Apr;6(2):82-5. doi: 10.4103/0974-777X.132053.


Intravenous immunoglobulin (IVIG) has been utilized in patients with recurrent and refractory Clostridium difficile colitis. It is increasingly being used in patients with initial clinical presentation of severe colitis. Herein, we report a case of severe C. Difficile colitis successfully treated with IVIG with a review of the medical literature to identify the optimal timing and clinical characteristics for this treatment strategy.

Keywords: Clostridium difficile; Colitis; Intravenous immunoglobulin.

Publication types

  • Case Reports