[Severe lactic acidosis revealing hematologic malignancy]

A Ouchikhe; J-L Le Bivic; O Longuet; J Maindivide; J-F Vincent

doi:10.1016/j.annfar.2014.05.005

[Severe lactic acidosis revealing hematologic malignancy]

Ann Fr Anesth Reanim. 2014 Jun;33(6):430-2. doi: 10.1016/j.annfar.2014.05.005. Epub 2014 Jun 10.

[Article in French]

Authors

A Ouchikhe¹, J-L Le Bivic², O Longuet², J Maindivide², J-F Vincent²

Affiliations

¹ Service de réanimation polyvalente, centre hospitalier Saintonge, 11, boulevard Ambroise-Paré, 17100 Saintes, France. Electronic address: a.ouchikhe@ch-saintonge.fr.
² Service de réanimation polyvalente, centre hospitalier Saintonge, 11, boulevard Ambroise-Paré, 17100 Saintes, France.

PMID: 24927632
DOI: 10.1016/j.annfar.2014.05.005

Abstract

A 75-year-old woman is hospitalised for sepsis. The diagnosis of cholecystitis is made and an antibiotic therapy is debuted. The clinical worsening leads to realise an urgent cholecystectomy. A sepsis like shock persisted. The antibiotherapy was changed and a second abdominal look made. A severe lactic acidosis persisted since the cholecystectomy despite a continuous hemofiltration. The diagnosis of type B lactic acidosis secondary to malignancy was suspected. An osteomedullar biopsy revelled B-cell lymphoma EBV induced.

Keywords: Acidose lactique; Epstein-Barr virus; Hematologic malignancy; Hémopathie; Lactic acidosis; Virus d’Epstein-Barr.

Publication types

Case Reports
English Abstract

MeSH terms

Acidosis, Lactic / diagnosis
Acidosis, Lactic / etiology*
Aged
Anti-Bacterial Agents / therapeutic use
Cholecystitis / complications
Epstein-Barr Virus Infections / complications
Female
Hematologic Neoplasms / complications*
Hematologic Neoplasms / diagnosis
Hemofiltration
Humans
Lymphoma, B-Cell / complications*
Lymphoma, B-Cell / diagnosis
Sepsis / complications

Substances

Anti-Bacterial Agents