Recent developments in gold(I) coordination chemistry: luminescence properties and bioimaging opportunities

Chem Commun (Camb). 2014 Sep 18;50(72):10343-54. doi: 10.1039/c4cc03259d.

Abstract

The fascinating biological activity of gold coordination compounds has led to the development of a wide range of complexes. The precise biological action of such species is often poorly understood and the ability to map gold distribution in cellular environments is key. This article discusses the recent progress in luminescent Au(I) complexes whilst considering their utility in bioimaging and therapeutics.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Auranofin / chemistry
  • Auranofin / toxicity
  • Cell Line, Tumor
  • Cell Proliferation / drug effects
  • Coordination Complexes / chemistry*
  • Coordination Complexes / toxicity
  • Crystallography, X-Ray
  • Gold / chemistry*
  • Heterocyclic Compounds / chemistry
  • Humans
  • Mice
  • Microscopy, Confocal
  • Molecular Conformation
  • Spectrometry, Fluorescence

Substances

  • Coordination Complexes
  • Heterocyclic Compounds
  • Auranofin
  • Gold