Sensory biology: it takes Piezo2 to tango

Curr Biol. 2014 Jun 16;24(12):R566-R569. doi: 10.1016/j.cub.2014.05.011.


A trio of papers has resolved an outstanding controversy regarding the function of Merkel cells and their afferent nerve fiber partners. Merkel cells sense mechanical stimuli (through Piezo2), fire action potentials, and are sufficient to activate downstream sensory neurons.