Selective ratiometric detection of H2O2 in water and in living cells with boronobenzo[b]quinolizinium derivatives

Chem Commun (Camb). 2014 Aug 4;50(60):8242-5. doi: 10.1039/c4cc02283a.

Abstract

Boronobenzo[b]quinolizinium derivatives exhibit several favorable properties for the fluorimetric detection of hydrogen peroxide, namely quantitative transformation to a product whose emission maximum is well separated from the one of the substrate, water solubility, and the ability to operate in living cells.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Boron Compounds / chemistry*
  • Flow Cytometry
  • Fluorescent Dyes / chemistry*
  • HeLa Cells
  • Humans
  • Hydrogen Peroxide / analysis*
  • Hydrogen Peroxide / chemistry
  • Jurkat Cells
  • Molecular Structure
  • Quinazolines / chemistry*
  • Spectrometry, Fluorescence
  • Water / chemistry*

Substances

  • Boron Compounds
  • Fluorescent Dyes
  • Quinazolines
  • Water
  • Hydrogen Peroxide