Giant chorioangioma treated in utero via laser of feeding vessels with subsequent development of multifocal infantile hemangiomas

Fetal Pediatr Pathol. 2015 Feb;34(1):1-8. doi: 10.3109/15513815.2014.925018. Epub 2014 Jun 18.


We report a case of a giant placental chorioangioma (15.6 cm diameter) complicated by polyhydramnios and severe fetal heart failure. Fetoscopic laser occlusion of a dominant feeding vessel was performed at 29 weeks' gestation and partial devascularization was achieved. In the 33rd week of the pregnancy, the decision was made to preemptively deliver the fetus due to persistent signs of fetal cardiac failure. After birth, the infant developed multifocal infantile hemangiomas with extracutaneous involvement. We posit that the development of infantile hemangiomas may be linked to the presence of the large chorioangioma. Further study is required to ascertain if fetal treatment of the chorioangioma may have been an exacerbating factor.

Keywords: chorioangioma; fetal treatment; fetoscopy; hemangioma; placental tumor.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Female
  • Fetoscopy
  • Heart Failure / complications
  • Heart Failure / embryology*
  • Heart Failure / therapy*
  • Hemangioma / complications
  • Hemangioma / diagnosis*
  • Hemangioma / embryology
  • Hemangioma / therapy*
  • Humans
  • Infant, Newborn
  • Lasers
  • Male
  • Placenta Diseases / diagnosis*
  • Placenta Diseases / therapy*
  • Polyhydramnios / diagnosis*
  • Polyhydramnios / therapy*
  • Pregnancy
  • Pregnancy Complications, Neoplastic
  • Pregnancy Outcome
  • Treatment Outcome