Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
, 10 (8), 1729-37

The Bone-Implant Interface - Nanoscale Analysis of Clinically Retrieved Dental Implants

Affiliations
Case Reports

The Bone-Implant Interface - Nanoscale Analysis of Clinically Retrieved Dental Implants

Furqan Ali Shah et al. Nanomedicine.

Abstract

Evaluation of the fine structure of the bone-implant interface in humans is a prerequisite for a deepened understanding of structure-function relationships with nano-modified biomaterials. In this study, three clinically stable, yet retrieved, laser-modified dental implants were evaluated using histological and interface ultrastructural analyses. The cumulative results for all threads containing intact tissue showed remodeled Haversian bone with bone area and bone-implant contact in excess of 85% and 80%, respectively. Collagen fibrils, laid down parallel to the surface oxide layer, were mineralized by plate-like crystallites of stoichiometrically relevant (Ca/P ratios 1.30-1.67) bone-apatite. An overlap of titanium, oxygen, calcium and phosphorus signals indicated the gradual intermixing of bone-apatite and the nano-rough surface oxide. These results suggest that bone bonding to nano-textured titanium implant surfaces is promoted in human jaw-bone after functional loading.

From the clinical editor: In this study, newly developed and laser-modified titanium dental implants demonstrate strong evidence for implant-osseo integration basen on the surface and chemical analysis of three clinically stable dental implants.

Keywords: Bone bonding; Dental implant; Electron microscopy; Nano; Osseointegration; Ultrastructure.

Similar articles

See all similar articles

Cited by 6 PubMed Central articles

See all "Cited by" articles

Publication types

LinkOut - more resources

Feedback