Temperature-responsive telechelic dipalmitoylglyceryl poly(N-isopropylacrylamide) vesicles: real-time morphology observation in aqueous suspension and in the presence of giant liposomes

Chem Commun (Camb). 2014 Aug 7;50(61):8350-2. doi: 10.1039/c4cc03199g.


Telechelic α,ω-di(twin-tailed poly(N-isopropylacrylamides)) form polymersomes in water that increase in size by fusion when the water temperature exceeds the polymers cloud point temperature. Hybrid vesicles form in mixed suspensions of giant phospholipid liposomes and polymersomes by adsorption/fusion, and undergo further transformations, such as fission.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acrylic Resins / chemistry*
  • Lipid Bilayers / chemistry
  • Liposomes / chemistry*
  • Particle Size
  • Temperature
  • Water / chemistry


  • Acrylic Resins
  • Lipid Bilayers
  • Liposomes
  • Water
  • poly-N-isopropylacrylamide