Theory of mind in first degree relatives of individuals with bipolar disorder

Psychiatry Res. 2014 Oct 30;219(2):400-2. doi: 10.1016/j.psychres.2014.05.041. Epub 2014 Jun 2.


We assessed theory of mind (ToM) performance in unaffected first-degree relatives of individuals with bipolar disorder compared to healthy controls across several well recognised tasks. Results indicated that the former group were significantly impaired on the verbal but not visual or higher-order ToM tasks, suggesting that a verbal ToM deficit might be a useful endophenotypic marker for bipolar disorder.

Keywords: Endophenotypes; Mood disorders; Social cognition.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Bipolar Disorder / psychology*
  • Family / psychology*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Neuropsychological Tests
  • Theory of Mind*
  • Young Adult