Biomarkers of coronary artery disease: the promise of the transcriptome

Curr Cardiol Rep. 2014 Aug;16(8):513. doi: 10.1007/s11886-014-0513-4.


The last years have witnessed tremendous technical advances in the field of transcriptomics that enable the simultaneous assessment of nearly all transcripts expressed in a tissue at a given time. These advances harbor the potential to gain a better understanding of the complex biological systems and for the identification and development of novel biomarkers. This article will review the current knowledge of transcriptomics biomarkers in the cardiovascular field and will provide an overview about the promises and challenges of the transcriptomics approach for biomarker identification.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Biomarkers / analysis*
  • Coronary Artery Disease / diagnosis*
  • Coronary Artery Disease / genetics
  • Gene Expression Profiling / methods
  • Genomics / methods
  • Humans
  • Transcriptome*


  • Biomarkers