LI-RADS categorization of benign and likely benign findings in patients at risk of hepatocellular carcinoma: a pictorial atlas

AJR Am J Roentgenol. 2014 Jul;203(1):W48-69. doi: 10.2214/AJR.13.12169.


Objective: The purpose of this article is to review the imaging features and Liver Imaging Reporting and Data System (LI-RADS) categorization of benign and likely benign entities, including typical cirrhotic nodules, distinctive nodular observations, and benign entities that may simulate hepatocellular carcinoma.

Conclusion: LI-RADS is a system of standardized criteria for interpreting liver CT and MR images of patients at risk of hepatocellular carcinoma. Most of the observations in these patients are not malignant. With the development of fibrosis and cirrhosis, these benign entities may take on an altered appearance.

Keywords: LI-RADS; benign liver nodules; cirrhosis; classification of liver lesions; hepatocellular carcinoma.

Publication types

  • Review

MeSH terms

  • Adult
  • Aged
  • Carcinoma, Hepatocellular / diagnosis*
  • Carcinoma, Hepatocellular / pathology
  • Child
  • Diagnosis, Differential
  • Female
  • Humans
  • Image Interpretation, Computer-Assisted / standards*
  • Liver Cirrhosis / pathology*
  • Liver Neoplasms / diagnosis*
  • Liver Neoplasms / pathology
  • Magnetic Resonance Imaging*
  • Male
  • Middle Aged
  • Risk Factors
  • Tomography, X-Ray Computed*