Aortic valve reconstruction using autologous pericardium for patients aged less than 60 years

J Thorac Cardiovasc Surg. 2014 Sep;148(3):934-8. doi: 10.1016/j.jtcvs.2014.05.041. Epub 2014 May 21.


Objective: We have performed an original aortic valve reconstruction using autologous pericardium. The feasibility for patients aged less than 60 years is reviewed.

Methods: From April 2007 to April 2013, aortic valve reconstruction was performed in 108 patients aged less than 60 years. A total of 51 patients had aortic stenosis, 7 patients had annuloaortic ectasia, 7 patients had infective endocarditis, and 43 patients had aortic regurgitation. Fifty-seven patients had bicuspid valves, and 11 patients had unicuspid valves. There were 75 male and 33 female patients, with a mean age of 47.8 ± 11.2 years. Preoperative echocardiography showed an average peak pressure gradient of 86.1 ± 35.1 mm Hg with aortic stenosis. The surgical procedure is based on the independent tricuspid replacement using autologous pericardium. First, the distance between the commissures is measured using an original sizing apparatus, and then the pericardial cusp is trimmed using an original template and sutured to the annulus.

Results: There was no conversion to prosthetic valve replacement. There were no in-hospital mortalities. Postoperative echocardiography showed an average peak pressure gradient of 14.8 ± 7.8 mm Hg 1 week after surgery and 12.8 ± 3.1 mm Hg 4 years after surgery. One patient required reoperation because of infective endocarditis. The other 107 patients showed less than mild aortic regurgitation. No thromboembolic events were recorded. The mean follow-up period was 34.2 ± 15.7 months. Freedom from reoperation was 98.9% with 76 months of follow-up.

Conclusions: Original aortic valve reconstruction was feasible for patients aged less than 60 years. Long-term data will be disclosed in the future.

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Aortic Valve / abnormalities
  • Aortic Valve / diagnostic imaging
  • Aortic Valve / physiopathology
  • Aortic Valve / surgery*
  • Cardiac Surgical Procedures*
  • Feasibility Studies
  • Female
  • Heart Valve Diseases / diagnosis
  • Heart Valve Diseases / physiopathology
  • Heart Valve Diseases / surgery*
  • Hemodynamics
  • Humans
  • Male
  • Middle Aged
  • Pericardium / transplantation*
  • Plastic Surgery Procedures*
  • Retrospective Studies
  • Time Factors
  • Transplantation, Autologous
  • Treatment Outcome
  • Ultrasonography
  • Young Adult