Coexistence of papillary thyroid cancer and Hashimoto thyroiditis in children: report of 3 cases

J Ultrasound Med. 2014 Jul;33(7):1299-303. doi: 10.7863/ultra.33.7.1299.

Abstract

This report documents 3 pediatric papillary thyroid carcinoma cases with associated Hashimoto thyroiditis. In all 3 cases, hypoechoic nodules accompanied by multiple echogenic spots were noted on sonography of the thyroid. Hashimoto thyroiditis was suspected on the basis of positive thyroid autoantibody test results and pathologic examinations of thyroidectomy specimens, which revealed chronic thyroiditis with lymphocytic infiltration as the background of papillary thyroid carcinoma development. The potential for papillary carcinoma development warrants close follow-up, and meticulous sonographic examinations must be performed in children with Hashimoto thyroiditis.

Keywords: Hashimoto thyroiditis; children; fine-needle aspiration; papillary thyroid carcinoma; sonography; superficial structures.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Biopsy, Fine-Needle
  • Carcinoma / diagnostic imaging*
  • Carcinoma / epidemiology*
  • Carcinoma / pathology
  • Carcinoma, Papillary
  • Child
  • Comorbidity
  • Female
  • Hashimoto Disease / diagnostic imaging*
  • Hashimoto Disease / epidemiology*
  • Hashimoto Disease / pathology
  • Humans
  • Thyroid Cancer, Papillary
  • Thyroid Neoplasms / diagnostic imaging*
  • Thyroid Neoplasms / epidemiology*
  • Thyroid Neoplasms / pathology
  • Ultrasonography