The utility of neuroimaging in the differential diagnosis of parkinsonian syndromes

Semin Neurol. 2014 Apr;34(2):202-9. doi: 10.1055/s-0034-1381733. Epub 2014 Jun 25.


The differential diagnosis of parkinsonian syndromes can be challenging, particularly in early disease stages. However, prognosis and therapeutic regimes are not alike in Parkinson disease and atypical parkinsonism, and thus a correct diagnosis at the earliest possible stage is desirable. Over the past two decades, magnetic resonance imaging and radiotracer-based imaging techniques have proven to be helpful tools to enhance the accuracy of clinical diagnosis in these disorders. Here, we review recent advances in neuroimaging for the differential diagnosis of parkinsonian syndromes.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Brain / pathology*
  • Brain / physiopathology
  • Diagnosis, Differential
  • Diagnostic Imaging / methods*
  • Humans
  • Neuroimaging / methods*
  • Parkinsonian Disorders / diagnosis*
  • Parkinsonian Disorders / pathology
  • Parkinsonian Disorders / physiopathology