[Estimation of small intestinal bacterial overgrowth in patients with constipation and diarrhea irritable bowel syndrome]

Pol Merkur Lekarski. 2014 May;36(215):307-10.
[Article in Polish]


Irritable bowel syndrome (IBS) is one of the most common reason for gastroenterology consultations. The diverse in symptomatology of the disease comes from its rich etiopathogenesis. Recently studies talk about infectious etiology of IBS and because of that it is necessary to expand its diagnostics by small intestinal bacterial overgrowth (SIBO) test. The aim of this study was to evaluate the prevalence of small intestinal bacterial overgrowth in patients with constipation (IBS-C) and diarrhea (IBS-D) irritable bowel syndrome with regard to nutrition.

Materials and methods: The study involved 46 subjects (33 women and 13 men) in average age of 44 years, which were divided into two groups: diarrhea and constipation IBS. All patients underwent hydrogen breath test studying bacterial overgrowth in the small intestine. In addition, each person had fulfilled a feeding questionnaire.

Statistical analysis: Student's t-test, Pearson test.

Results: It has been shown that there is no statistical significances between the prevalence of SIBO in form of diarrheal IBS and constipation IBS and gender. Average value of increments of hydrogen in breath during the test was higher in IBS-C in comparison with IBS-D, which was the highest in the intestine bacterial overgrowth in patients with IBS-C. STATISTICAL ANALYSIS showed that there is no relationship between the type and frequency of consumption of milk, meat, fruit and vegetables, sweets and coffee and the prevalence of SIBO in form of diarrhea and constipation IBS.

Conclusions: The occurrence of constipation or diarrhea irritable bowel syndrome is not related to gender. SIBO is more common in patients with IBS-C than in IBS-D group. There is no relationship between the type of food consumed and the amount of SIBO in people with IBS. Type of food intake do not affect the status of the intestinal flora of people with IBS.

MeSH terms

  • Adolescent
  • Adult
  • Blind Loop Syndrome / diagnosis*
  • Blind Loop Syndrome / epidemiology
  • Breath Tests
  • Causality
  • Comorbidity
  • Constipation / epidemiology
  • Constipation / microbiology*
  • Diarrhea / epidemiology
  • Diarrhea / microbiology*
  • Feeding Behavior
  • Female
  • Humans
  • Hydrogen / analysis
  • Intestine, Small / microbiology*
  • Irritable Bowel Syndrome / epidemiology
  • Irritable Bowel Syndrome / microbiology*
  • Male
  • Middle Aged
  • Prevalence
  • Risk Factors
  • Surveys and Questionnaires
  • Young Adult


  • Hydrogen