Lupus anticoagulant and late onset seizures

Acta Neurol Scand. 1989 Feb;79(2):114-8. doi: 10.1111/j.1600-0404.1989.tb03721.x.


Lupus anticoagulant was found in the plasma of 4 patients who presented with late-onset epileptic seizures. Three of the patients had clinical or electroencephalographic evidence of focality. No significant cerebral pathological findings were detected by the computed tomogram except for an old infarction in one case. None of the patients fulfilled the diagnostic criteria for systemic lupus erythematosus. The relationship between late-onset seizures and the presence of lupus anticoagulant is discussed. The possible etiology of an ischemic episode due to hypercoagulability, expressed uniquely by seizures, is suggested.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Blood Coagulation Factors / blood
  • Blood Coagulation Factors / immunology*
  • Epilepsy / immunology*
  • Humans
  • Lupus Coagulation Inhibitor
  • Male
  • Middle Aged


  • Blood Coagulation Factors
  • Lupus Coagulation Inhibitor