Aortic stenosis and coronary artery disease: what do we know? What don't we know? A comprehensive review of the literature with proposed treatment algorithms

Eur Heart J. 2014 Aug 14;35(31):2069-82. doi: 10.1093/eurheartj/ehu247. Epub 2014 Jun 26.


Aortic valve stenosis is the most common form of valvular heart disease in the elderly population and occurs frequently in conjunction with coronary artery disease. The standard treatment option for patients with these two conditions has been surgical aortic valve replacement and coronary artery bypass grafting. The arrival of transcatheter aortic valve replacement has considerably shifted the treatment paradigms. Nevertheless, a lot of questions remain unanswered regarding the management of coronary artery disease in the setting of the transcatheter options for severe aortic stenosis. This article includes a comprehensive review of the literature and seeks to describe the actual knowledge on the topic of aortic stenosis and concomitant coronary artery disease.

Keywords: Aortic stenosis; Coronary artery disease; Percutaneous coronary intervention; Surgical aortic valve replacement; Transcatheter aortic valve replacement.

Publication types

  • Review

MeSH terms

  • Adult
  • Aged
  • Algorithms
  • Aortic Valve Stenosis / complications*
  • Aortic Valve Stenosis / surgery
  • Combined Modality Therapy
  • Coronary Artery Disease / complications*
  • Coronary Artery Disease / surgery
  • Coronary Circulation / physiology
  • Heart Valve Prosthesis Implantation
  • Humans
  • Middle Aged
  • Myocardial Infarction / etiology
  • Percutaneous Coronary Intervention
  • Postoperative Complications / etiology
  • Time-to-Treatment
  • Transcatheter Aortic Valve Replacement
  • Treatment Outcome
  • Vascular Calcification / complications