Genital ulcers: it is not always simplex …

Int J STD AIDS. 2015 Jan;26(1):72-3. doi: 10.1177/0956462414541241. Epub 2014 Jun 26.


Patients with vulval aphthae, also termed Lipschütz ulcers, often present to genitourinary medicine clinics. Typically, these ulcers present as acute, painful, vulval ulcers in young women and adolescents. The aetiology is unknown, and often these ulcers are accompanied by flu-like symptoms. Previous case reports have linked such lesions to acute viral infections such as Epstein-Barr virus, cytomegalovirus and influenza A. We report the first case of influenza B virus and adenovirus infections associated with this presentation.

Keywords: Diagnosis; Lipschutz ulcers; adenovirus; adolescents; genital ulcers; influenza B virus; virology; women.

Publication types

  • Case Reports

MeSH terms

  • Acyclovir / therapeutic use
  • Adolescent
  • Antiviral Agents / therapeutic use
  • Female
  • Humans
  • Influenza B virus / isolation & purification*
  • Influenza, Human / complications*
  • Influenza, Human / diagnosis
  • Influenza, Human / drug therapy
  • Polymerase Chain Reaction
  • Skin Ulcer / etiology
  • Skin Ulcer / pathology
  • Treatment Outcome
  • Ulcer / diagnosis*
  • Ulcer / virology
  • Vulvar Diseases / diagnosis*
  • Vulvar Diseases / drug therapy
  • Vulvar Diseases / virology


  • Antiviral Agents
  • Acyclovir