Complete Genome Sequences of Two Prolific Biofilm-Forming Staphylococcus aureus Isolates Belonging to USA300 and EMRSA-15 Clonal Lineages

J S Sabirova; B B Xavier; J-P Hernalsteens; H De Greve; M Ieven; H Goossens; S Malhotra-Kumar

doi:10.1128/genomeA.00610-14

Complete Genome Sequences of Two Prolific Biofilm-Forming Staphylococcus aureus Isolates Belonging to USA300 and EMRSA-15 Clonal Lineages

Genome Announc. 2014 Jun 26;2(3):e00610-14. doi: 10.1128/genomeA.00610-14.

Authors

J S Sabirova¹, B B Xavier¹, J-P Hernalsteens², H De Greve, M Ieven¹, H Goossens¹, S Malhotra-Kumar³

Affiliations

¹ Department of Medical Microbiology, Vaccine & Infectious Disease Institute, Universiteit Antwerpen, Antwerp, Belgium.
² Viral Genetics Research Group, Vrije Universiteit Brussel, Brussels, Belgium.
³ Department of Medical Microbiology, Vaccine & Infectious Disease Institute, Universiteit Antwerpen, Antwerp, Belgium surbhi.malhotra@uantwerpen.be.

Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) causes serious infections that are even more difficult to treat when associated with a biofilm phenotype that facilitates evasion of the host immune system and antibiotics. As a first step toward understanding the mechanisms underlying biofilm formation, we sequenced the genomes of two prolific biofilm-forming strains belonging to the two most important globally disseminated clonal lineages, USA300 and EMRSA-15.