Spasmodic dysphonia: let's look at that again

J Voice. 2014 Nov;28(6):694-9. doi: 10.1016/j.jvoice.2014.03.007. Epub 2014 Jun 24.


G. Paul Moore influenced the study of spasmodic dysphonia (SD) with his 1960 publication that examined the neurological, medical, and vocal fold behavior in a group of patients with adductor spasmodic dysphonia (ADSD). This review of advances in the diagnosis and treatment of SD follows a time line of research that can be traced in part to the early work of Moore et al. This article reviews the research in ADSD over the past 50 plus years. The capstone events that brought SD to its present day level of management by laryngologists and speech-language pathologists are highlighted. A look to the future to understand more of the disorder is offered for this debilitating disorder.

Keywords: Adductor spasmodic dysphonia; Botulinum toxin; G. Paul Moore.

Publication types

  • Historical Article
  • Review

MeSH terms

  • Botulinum Toxins / therapeutic use
  • Dysphonia* / diagnosis
  • Dysphonia* / history
  • Dysphonia* / physiopathology
  • Dysphonia* / psychology
  • Dysphonia* / therapy
  • History, 20th Century
  • History, 21st Century
  • Humans
  • Laryngeal Muscles / drug effects
  • Laryngeal Muscles / physiopathology*
  • Neuromuscular Agents / therapeutic use
  • Phonation* / drug effects
  • Prognosis
  • Spasm* / diagnosis
  • Spasm* / history
  • Spasm* / physiopathology
  • Spasm* / psychology
  • Spasm* / therapy
  • Speech Acoustics*
  • Speech-Language Pathology / methods
  • Voice Quality* / drug effects


  • Neuromuscular Agents
  • Botulinum Toxins