Endocrine Scintigraphy With Hybrid SPECT/CT

Endocr Rev. 2014 Oct;35(5):717-46. doi: 10.1210/er.2013-1030. Epub 2014 Jun 30.


Nuclear medicine imaging of endocrine disorders takes advantage of unique cellular properties of endocrine organs and tissues that can be depicted by targeted radiopharmaceuticals. Detailed functional maps of biodistributions of radiopharmaceutical uptake can be displayed in three-dimensional tomographic formats, using single photon emission computed tomography (CT) that can now be directly combined with simultaneously acquired cross-sectional anatomic maps derived from CT. The integration of function depicted by scintigraphy and anatomy with CT has synergistically improved the efficacy of nuclear medicine imaging across a broad spectrum of clinical applications, which include some of the oldest imaging studies of endocrine dysfunction.

Publication types

  • Review

MeSH terms

  • Endocrine System Diseases / diagnostic imaging*
  • Humans
  • Multimodal Imaging / instrumentation
  • Multimodal Imaging / methods*
  • Tomography, Emission-Computed, Single-Photon / instrumentation
  • Tomography, Emission-Computed, Single-Photon / methods*
  • Tomography, X-Ray Computed / instrumentation
  • Tomography, X-Ray Computed / methods*