Disseminated verruciform xanthoma: a case report

Cutis. 2014 Jun;93(6):307-10.


Verruciform xanthomas (VXs) are rare mucocutaneous lesions that can appear in isolation or in association with chronic inflammation, systemic diseases, or metabolic abnormalities. We report the case of a patient who presented with disseminated VX with oral, cutaneous, and genital involvement without an obvious underlying cause. Treatments including salicylic acid 40%, high-potency topical corticosteroids, antibiotics, and chlorhexidine failed to improve the lesions; however, the patient was satisfied with the cosmetic results of serial shave excisions. This case highlights a rare entity of unknown etiology. Further studies are needed to determine the cause of this mucocutaneous entity so that more effective treatment modalities can be elucidated.

Publication types

  • Case Reports

MeSH terms

  • Adrenal Cortex Hormones / administration & dosage
  • Back / pathology*
  • Humans
  • Keratosis / pathology
  • Male
  • Middle Aged
  • Penile Diseases / drug therapy
  • Penile Diseases / pathology*
  • Salicylic Acid / administration & dosage
  • Skin Diseases / drug therapy
  • Skin Diseases / pathology*
  • Tongue Diseases / drug therapy
  • Tongue Diseases / pathology*
  • Treatment Outcome
  • Xanthomatosis / drug therapy
  • Xanthomatosis / pathology*


  • Adrenal Cortex Hormones
  • Salicylic Acid