New affinity-based probes for capturing flavonoid-binding proteins

Chem Commun (Camb). 2014 Aug 25;50(66):9387-9. doi: 10.1039/c4cc04557b.


Flavonoid-bearing probes have been designed and synthesized to explore their ability to selectively capture target proteins or biosynthetic enzymes under oxidative activation. A proof-of-concept study using biotinylated (epi)catechin-bearing affinity-based probes herein demonstrates the ability of these probes to capture the LDOX flavonoid enzyme using sodium periodate as the oxidant.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Affinity Labels*
  • Electrophoresis, Polyacrylamide Gel
  • Flavonoids / chemistry*
  • Proteins / chemistry*


  • Affinity Labels
  • Flavonoids
  • Proteins