Evidence for supplemental treatments in androgenetic alopecia

J Drugs Dermatol. 2014 Jul;13(7):809-12.


Currently, topical minoxidil and finasteride are the only treatments that have been FDA approved for the treatment of female pattern hair loss and androgenetic alopecia. Given the incomplete efficacy and sife effect profile of these medications, some patients utilize alternative treatments to help improve this condition. In this review, we illustrate the scientific evidence underlying the efficacy of these alternative approaches, including biotin, caffeine, melatonin, a marine extract, and zinc.

MeSH terms

  • Alopecia / drug therapy*
  • Alopecia / pathology
  • Biological Products / therapeutic use
  • Biotin / therapeutic use
  • Caffeine / therapeutic use
  • Female
  • Humans
  • Male
  • Melatonin / therapeutic use
  • Zinc / therapeutic use


  • Biological Products
  • Caffeine
  • Biotin
  • Zinc
  • Melatonin