Involuntary detrusor contraction is a frequent finding in patients with recurrent urinary tract infections

Urol Int. 2014;93(1):67-73. doi: 10.1159/000356063. Epub 2014 Feb 26.

Abstract

Objective: To check whether subtle voiding dysfunction is related to recurrent urinary tract infection (rUTI).

Methods: 254 consecutive patients with at least four episodes of urinary tract infection (UTI) were studied. At least three repeat urodynamic evaluations with an additional ice water test to maximize the detection of involuntary detrusor contraction (IDC) were used. Stress urinary incontinence cases were used as controls. Nonparametric univariate and multivariate analyses were used for statistics.

Results: IDC was detected in 83.6% of patients in the rUTI group and in 31.7% in the control group. IDC was <15 cm H2O in 54.7% whereas high-amplitude (>50 cm H2O) IDC was observed in 6.8% in the rUTI group. Female urinary tract obstruction was diagnosed in 16.8% of patients in the rUTI group and in 7.9% in the control group. Residual volume, PdetQmax and Qmax were not predictive of UTI recurrence. Symptoms were similar in both groups.

Conclusions: Patients with rUTI present with covert bladder dysfunctions represented by detrusor overactivity.

MeSH terms

  • Adult
  • Female
  • Humans
  • Middle Aged
  • Multivariate Analysis
  • Muscle Contraction
  • Muscle, Smooth / physiopathology
  • Prospective Studies
  • Recurrence
  • Surveys and Questionnaires
  • Urinary Bladder / pathology*
  • Urinary Bladder, Overactive / pathology*
  • Urinary Incontinence, Stress / physiopathology
  • Urinary Tract Infections / pathology*
  • Urination Disorders / physiopathology
  • Urodynamics
  • Water

Substances

  • Water