S2O8(2-)/UV-C and H2O2/UV-C treatment of Bisphenol A: assessment of toxicity, estrogenic activity, degradation products and results in real water

Chemosphere. 2015 Jan;119 Suppl:S115-23. doi: 10.1016/j.chemosphere.2014.06.020. Epub 2014 Jul 8.

Abstract

The performance of S2O8(2-)/UV-C and H2O2/UV-C treatments was investigated for the degradation and detoxification of Bisphenol A (BPA). The acute toxicity of BPA and its degradation products was examined with the Vibrio fischeri bioassay, whereas changes in estrogenic activity were followed with the Yeast Estrogen Screen (YES) assay. LC and LC-MS/MS analyses were conducted to determine degradation products evolving during photochemical treatment. In addition, BPA-spiked real freshwater samples were also subjected to S2O8(2-)/UV-C and H2O2/UV-C treatment to study the effect of a real water matrix on BPA removal and detoxification rates. BPA removal in pure water was very fast (⩽7 min) and complete via both H2O2/UV-C and S2O8(2-)/UV-C treatment, accompanied with rapid and significant mineralization rates ranging between 70% and 85%. V.fischeri bioassay results indicated that degradation products being more toxic than BPA were formed at the initial stages of H2O2/UV-C whereas a rapid and steady reduction in toxicity was observed during S2O8(2-)/UV-C treatment in pure water. UV-C treatment products exhibited a higher estrogenic activity than the original BPA solution while the estrogenicity of BPA was completely removed during H2O2/UV-C and S2O8(2-)/UV-C treatments parallel to its degradation. 3-methylbenzoic and 4-sulfobenzoic acids, as well as the ring opening products fumaric, succinic and oxalic acids could be identified as degradation products. BPA degradation required extended treatment periods (>20 min) and TOC removals were considerably retarded (by 40%) in the raw freshwater matrix most probably due to its natural organic matter content (TOC=5.1 mg L(-1)). H2O2/UV-C and S2O8(2-)/UV-C treatment in raw freshwater did not result in toxic degradation products.

Keywords: Acute toxicity; Bisphenol A; Degradation products; Real freshwater matrix; S(2)O(8)(2−)/UV-C and H(2)O(2)/UV-C treatments; Yeast Estrogen Screen (YES) assay.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aliivibrio fischeri / drug effects
  • Aliivibrio fischeri / metabolism
  • Benzhydryl Compounds* / chemistry
  • Benzhydryl Compounds* / radiation effects
  • Benzhydryl Compounds* / toxicity
  • Carboxylic Acids / chemistry
  • Chromatography, Liquid
  • Estrogen Receptor alpha / metabolism
  • Estrogens* / chemistry
  • Estrogens* / radiation effects
  • Estrogens* / toxicity
  • Fresh Water
  • Hydrogen Peroxide / chemistry*
  • Oxidants / chemistry
  • Phenols* / chemistry
  • Phenols* / radiation effects
  • Phenols* / toxicity
  • Saccharomyces cerevisiae / genetics
  • Sodium Compounds / chemistry*
  • Sulfates / chemistry*
  • Tandem Mass Spectrometry
  • Ultraviolet Rays*
  • Water Pollutants, Chemical* / chemistry
  • Water Pollutants, Chemical* / radiation effects
  • Water Pollutants, Chemical* / toxicity
  • Water Purification / methods

Substances

  • Benzhydryl Compounds
  • Carboxylic Acids
  • Estrogen Receptor alpha
  • Estrogens
  • Oxidants
  • Phenols
  • Sodium Compounds
  • Sulfates
  • Water Pollutants, Chemical
  • Hydrogen Peroxide
  • sodium persulfate
  • bisphenol A