Necrotizing fasciitis after breast augmentation: rapid microbiologic detection by using sonication of removed implants and microcalorimetry

Am J Clin Pathol. 2014 Aug;142(2):269-72. doi: 10.1309/AJCPNA1ZKVK7PHUD.

Abstract

Objectives: To describe the use of sonication and microcalorimetry in diagnosing necrotizing fasciitis in a 27-year-old woman with bilateral breast implants.

Methods: The removed breast implants were subjected to sonication and microcalorimetry. The microcalorimetry findings were correlated with conventional microbiologic methods. The time to detection of infection was noted.

Results: The patient had painful cellulitis of the right breast that enlarged within hours. Her C-reactive protein level was increased. Chest radiograph showed gas formation in the soft tissue lateral of the right breast. Surgery was performed: 300 mL (right breast) and 100 mL (left breast) of serous-purulent fluid were evacuated. Streptococcus pyogenes was cultured from the fluid 1 day after clinical presentation. Infection was diagnosed by microcalorimetry of sonication fluid in 1 hour and 21 minutes. The microcalorimetry curve from the right implant reached the peak earlier than did the left implant.

Conclusion: Microcalorimetry will have a benefit in conditions in which rapid diagnosis of infection is important.

Keywords: Breast implant; Microcalorimetry; Necrotizing fasciitis; Sonication.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Breast Implants / adverse effects*
  • C-Reactive Protein / metabolism
  • Calorimetry / methods
  • Early Diagnosis
  • Fasciitis, Necrotizing / diagnosis
  • Fasciitis, Necrotizing / microbiology*
  • Female
  • Humans
  • Sonication / methods

Substances

  • C-Reactive Protein