Vaccine allergy

Immunol Allergy Clin North Am. 2014 Aug;34(3):597-613, ix. doi: 10.1016/j.iac.2014.04.004.


Overdiagnosis of vaccine allergy is considered a major public health problem. This article discusses the different types of allergic reactions after immunization based on the timing (immediate vs nonimmediate) and the extent of the reaction (local vs systemic). The vaccine components potentially responsible for an allergic reaction are discussed, as well as the management of patients with a history of reaction to a specific vaccine and those with a history of allergy to one of the vaccine components.

Keywords: Children; Egg; Gelatin; Hypersensitivity; Toxoids; Vaccine allergy; Vaccine components.

Publication types

  • Review

MeSH terms

  • Disease Management
  • Humans
  • Hypersensitivity / diagnosis*
  • Hypersensitivity / etiology
  • Hypersensitivity / prevention & control*
  • Risk Factors
  • Vaccines / adverse effects*
  • Vaccines / classification


  • Vaccines