Place of excipients in systemic drug allergy

Immunol Allergy Clin North Am. 2014 Aug;34(3):671-9, x. doi: 10.1016/j.iac.2014.04.006.

Abstract

Hypersensitivity reactions to excipients contained in drugs are rare but can be severe or confusing. With regard to generic versus brand drug, often the ingredients are different; for each DHR, we recommend that the physician exercises caution in considering which brand drug or generic was administered and in listing all medicine components and not only the active drug.

Keywords: Carboxymethylcellulose; Excipients; Insulin; Sodium benzoate; Sulfites; Vaccines.

Publication types

  • Review

MeSH terms

  • Drug Hypersensitivity / diagnosis*
  • Drug Hypersensitivity / etiology*
  • Excipients / adverse effects*
  • Excipients / classification
  • Humans

Substances

  • Excipients