Venous thromboembolism prophylaxis guideline compliance: a pilot study of augmented medication charts

Ir J Med Sci. 2015 Jun;184(2):469-74. doi: 10.1007/s11845-014-1148-6. Epub 2014 Jul 15.

Abstract

Introduction: Venous thromboembolism (VTE) is a common complication of hospital admission. The incidence of hospital-acquired deep vein thrombosis is approximately 10-40% amongst medical and general surgical patients without prophylaxis. Pulmonary embolism accounts for 5-10% of deaths in hospitalised patients, making hospital-acquired VTE the most common preventable cause of in-hospital death. Studies suggest that prophylactic measures are widely under- and inappropriately used.

Aims: We hypothesised that the introduction of a medication chart with a dedicated VTE prophylaxis section would improve compliance with local guidelines.

Methods: Trial medication charts were piloted over a 4-week period in one surgical and two medical wards. Data on compliance with hospital guidelines were collected before and after introduction using a detailed chart review. The difference in prescribing compliance was assessed with the Chi-squared test.

Results: 70 patients were assessed before and 38 after the introduction of the new charts. Initially, only 58.6% (n = 41) of patients' prescriptions were in compliance with local guidelines. In 28.6% (n = 20) of patients, VTE prophylaxis was needed and not prescribed. 7.1% (n = 5) of patients were prescribed an inappropriately low dose of low molecular weight heparin (LMWH) prophylaxis. 2.9% (n = 2) of patients were prescribed inappropriately high dose of LMWH prophylaxis. After introduction of the new medication chart, compliance with guidelines rose to 71% (n = 27, p = 0.09).

Conclusion: Compliance with VTE guidelines is inadequate. Medication charts with specific sections on VTE assessment and prophylaxis may increase compliance with guidelines.

MeSH terms

  • Anticoagulants / administration & dosage
  • Contraindications
  • Decision Support Techniques*
  • Guideline Adherence*
  • Heparin, Low-Molecular-Weight / administration & dosage
  • Hospitalization
  • Humans
  • Medical Audit
  • Medical Records*
  • Middle Aged
  • Pilot Projects
  • Practice Guidelines as Topic
  • Pulmonary Embolism / prevention & control*
  • Risk Assessment / methods
  • Venous Thromboembolism / prevention & control*
  • Venous Thrombosis / prevention & control*

Substances

  • Anticoagulants
  • Heparin, Low-Molecular-Weight