Neuroendocrine breast carcinoma metastatic to the liver: Report of a case and review of the literature

Konstantinos Manes; Spyridon Delis; Nikolaos Papaspyrou; Ioanna Ghiconti; Christos Dervenis

doi:10.1016/j.ijscr.2014.05.006

Neuroendocrine breast carcinoma metastatic to the liver: Report of a case and review of the literature

Int J Surg Case Rep. 2014;5(8):540-3. doi: 10.1016/j.ijscr.2014.05.006. Epub 2014 Jun 24.

Authors

Konstantinos Manes¹, Spyridon Delis², Nikolaos Papaspyrou², Ioanna Ghiconti³, Christos Dervenis²

Affiliations

¹ Surgical Department, "Konstantopouleio" General Hospital, Athens, Greece. Electronic address: dinos_manes@yahoo.com.
² Surgical Department, "Konstantopouleio" General Hospital, Athens, Greece.
³ Pathology Department, "Konstantopouleio" General Hospital, Athens, Greece.

Abstract

Introduction: Primary neuroendocrine breast carcinoma (NEBC) is a rare entity of breast cancer.

Presentation of case: We herein report a case of right hepatectomy for a NEBC liver metastasis.

Discussion: Little is known about its evolution, bilologic behavior and optimal treatment. Its malignant potential has been addressed in few reports, with cases of metachronous metastases in diverse sites, even years following treatment of the breast primarily.

Conclusion: Treating this kind of cancer implies both breast and hepatic surgery. Primary neuroendocrine breast carcinoma (NEBC) is a rare entity of breast cancer. Little is known about its evolution, biologic behavior and optimal treatment. Its malignant potential has been addressed in few reports, with cases of metachronous metastases in diverse sites, even years following treatment of the breast primarily. We herein report a case of right hepatectomy for a NEBC liver metastasis.

Keywords: Breast cancer; Liver metastasis; Neuroendocrine breast carcinoma.