Treatment of acute pulmonary embolism: update on newer pharmacologic and interventional strategies

Biomed Res Int. 2014:2014:410341. doi: 10.1155/2014/410341. Epub 2014 Jun 15.

Abstract

Acute pulmonary embolism (PE) is a common complication in hospitalized patients, spanning multiple patient populations and crossing various therapeutic disciplines. Current treatment paradigm in patients with massive PE mandates prompt risk stratification with aggressive therapeutic strategies. With the advent of endovascular technologies, various catheter-based thrombectomy and thrombolytic devices are available to treat patients with massive or submassive PE. In this paper, a variety of newer treatment strategies for PE are analyzed, with special emphasis on various interventional treatment strategies. Clinical evidence for utilizing endovascular treatment modalities, based on our institutional experience as well as a literature review, is provided.

Publication types

  • Review
  • Retracted Publication

MeSH terms

  • Adult
  • Angiography
  • Female
  • Fibrinolysis*
  • Humans
  • Male
  • Middle Aged
  • Pulmonary Embolism / diagnostic imaging
  • Pulmonary Embolism / drug therapy*
  • Pulmonary Embolism / physiopathology
  • Pulmonary Embolism / surgery*
  • Thrombolytic Therapy*