[Hydatidiform mole and malignant trophoblastic tumors initiated by hydatidiform mole. Standards and innovation of diagnosis and treatment]

Vopr Onkol. 2014;60(3):396-401.
[Article in Russian]

Abstract

Malignant trophoblastic tumors are hormone and hormone-dependent allografts initiated by, in the most cases, hydatidiform mole. The absence of methodological principles for monitoring of women after evacuation of hydatidiform mole often leads to late detection of the disease, inadequate chemotherapy conducted in clinics with no experience of treatment, followed by the development of drug-resistant tumors and worse prognosis. This paper analyzes the problem at the moment.

Publication types

  • Lecture

MeSH terms

  • Adolescent
  • Adult
  • Antineoplastic Agents / therapeutic use*
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Female
  • Humans
  • Hydatidiform Mole / diagnosis*
  • Hydatidiform Mole / epidemiology
  • Hydatidiform Mole / pathology
  • Hydatidiform Mole / therapy*
  • Hysterectomy
  • Middle Aged
  • Pregnancy
  • Prognosis
  • Trophoblastic Neoplasms / diagnosis*
  • Trophoblastic Neoplasms / epidemiology
  • Trophoblastic Neoplasms / pathology
  • Trophoblastic Neoplasms / therapy*
  • Ukraine / epidemiology
  • Uterine Neoplasms / diagnosis*
  • Uterine Neoplasms / epidemiology
  • Uterine Neoplasms / pathology
  • Uterine Neoplasms / therapy*
  • Young Adult

Substances

  • Antineoplastic Agents