Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2014;4(2):83-8.
doi: 10.5681/bi.2014.007. Epub 2014 Jun 11.

Effects of Probiotic Yogurt Consumption on Inflammatory Biomarkers in Patients With Type 2 Diabetes

Affiliations
Free PMC article

Effects of Probiotic Yogurt Consumption on Inflammatory Biomarkers in Patients With Type 2 Diabetes

Majid Mohamadshahi et al. Bioimpacts. .
Free PMC article

Abstract

Introduction: The role of inflammatory cytokines in diabetes and its complications has been shown in some studies. The purpose of this study was to compare the effect of probiotic and conventional yogurt on inflammatory markers in patients with type 2 diabetes.

Methods: Forty-four patients with type 2 diabetes were participated in this randomized, double-blind controlled clinical trial and assigned to two intervention and control groups. The subjects in the intervention group consumed 300 g/d probiotic yogurt and subjects in the control group consumed 300 g/d conventional yogurt for 8 weeks. Anthropometric indices, dietary intakes, and serum levels of glucose, HbA1c, IL-6, TNF-α and hs-CRP were evaluated at the beginning and end of the intervention.

Results: For anthropometric indices and dietary intakes, no significant differences were seen within and between groups post intervention (p> 0.05). The consumption of probiotic yogurt caused significant decrease in HbA1c and TNF-α levels (p= 0.032 and p= 0.040, respectively) in the intervention group.

Conclusion: It is suggested that probiotic yogurt may be used as an alternative prevention approach and treatment method to control diabetic complications.

Keywords: Glycosylated hemoglobin; Inflammatory biomarkers; Probiotic; Type 2 diabetes.

Similar articles

See all similar articles

Cited by 19 articles

See all "Cited by" articles

References

    1. Azimi-Nezhad M, Ghayour-Mobarhan M, Parizadeh MR, Safarian M, Esmaeili H, Parizadeh SM. et al. Prevalence of type 2 diabetes mellitus in Iran and its relationship with gender, urbanisation, education, marital status and occupation. Singapore Med J. 2008;49:571–576. - PubMed
    1. Pearson TA. New tools for coronary risk assessment: what are their advantages and limitations? Circulation. 2002;105:886–892. - PubMed
    1. Goldberg RB. Cytokine and cytokine-like inflammation markers, endothelial dysfunction, and imbalance coagulation in development of diabetes and its complications. J Clin Endocrinol Metab. 2009;94:3171–82. - PubMed
    1. Bertoni AG, Burke GL, Owusu JA, Carnethon MR, Vaidya D, Barr RG. et al. Inflammation and the incidence of type 2 diabetes: the Multi-Ethnic Study of Atherosclerosis (MESA) Diabetes Care. 2010;33:804–810. - PMC - PubMed
    1. Coppola G, Corrado E, Muratori I, Tantillo R, Vitale G, Lo Coco L. et al. Increased levels of C-reactive protein and fibrinogen influence the risk of vascular events in patients with NIDDM. Int J Cardiol. 2006;106:16–20. - PubMed

LinkOut - more resources

Feedback