Hand, foot and mouth disease caused by coxsackievirus A6, Beijing, 2013

Pediatr Infect Dis J. 2014 Dec;33(12):1302-3. doi: 10.1097/INF.0000000000000467.


Specimens and clinical data were collected from 243 hand, foot and mouth disease patients in Beijing in 2013. In total, 130 stool specimens were genotyped for enterovirus. Hand, foot and mouth disease was mainly detected in suburban areas and at the edges of urban areas between May and August. Coxsackievirus (CV) A6 replaced enterovirus (EV) 71 and CVA16, becoming the main causative agent of hand, foot and mouth disease. CVA6 infection led to significantly reduced fever duration and glucose levels compared with EV71 infection.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • China / epidemiology
  • Enterovirus / classification
  • Enterovirus / isolation & purification*
  • Feces / virology
  • Female
  • Genotype
  • Hand, Foot and Mouth Disease / epidemiology
  • Hand, Foot and Mouth Disease / virology*
  • Humans
  • Infant
  • Male
  • Molecular Epidemiology
  • Seasons
  • Suburban Population
  • Young Adult