Choosing treatment for depression in older adults and evaluating response

Clin Geriatr Med. 2014 Aug;30(3):535-51. doi: 10.1016/j.cger.2014.04.005. Epub 2014 Jun 12.


An update is provided on the current information regarding late life depression with regard to assessment, clinical implications, and treatment recommendations. Several treatments are considered evidence-based, but when deployed into field trials, the efficacy of these treatments falls short. It is thought that the lower impact in community trials is due in large part to patient, clinical, environmental, socio-economic, and cognitive correlates that influence treatment response. The aim is to assist providers in making decisions about what type of treatment to recommend based on a sound assessment of these clinical correlates.

Keywords: Geriatrics; Late life depression; Mood disorders; Psychotherapy; Targeted treatment.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Aged
  • Decision Support Techniques
  • Depression / therapy*
  • Humans
  • Psychotherapy, Group / methods*
  • Quality-Adjusted Life Years*