There has been increasing emphasis on care and treatment for persons with human immunodeficiency virus (HIV) in the United States during the past decade,, including the use of antiretroviral therapy for increasing survival and decreasing transmission. Accurate HIV diagnosis data recently became available for all states, allowing for the first time an examination of long-term national trends. These data can be used to monitor awareness of serostatus among persons living with HIV, primary prevention efforts, and testing initiatives. We examined trends in HIV diagnoses from 2002–2011 in the United States using data from the National HIV Surveillance System of the US Centers for Disease Control and Prevention (CDC).