Detecting monoclonal light chains in urine: microLC-ESI-Q-TOF mass spectrometry compared to immunofixation electrophoresis

Br J Haematol. 2014 Nov;167(3):437-8. doi: 10.1111/bjh.13003. Epub 2014 Jul 7.

Authors

Chad M Botz¹, David R Barnidge, David L Murray, Jerry A Katzmann

Affiliation

¹ Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.

PMID: 25039602
DOI: 10.1111/bjh.13003

No abstract available

Keywords: laboratory haematology; mass spectrometry; methodology; myeloma.

Publication types

Comparative Study
Evaluation Study
Letter

MeSH terms

Antibodies, Monoclonal / urine*
Humans
Immunoelectrophoresis
Immunoglobulin Light Chains / urine*
Microchemistry
Molecular Weight
Osmolar Concentration
Proteinuria / immunology
Proteinuria / urine*
Spectrometry, Mass, Electrospray Ionization* / economics
Urinalysis / economics
Urinalysis / methods
Waldenstrom Macroglobulinemia / urine

Substances

Antibodies, Monoclonal
Immunoglobulin Light Chains