In the article there have been analyzed the materials obtained in the study of human health state on the results of the study of immunological status. It was shown that the In mass hygienic studies the detection of the state of the human immune system has been shown to be the one of the most promising methods for the determination of human health state, as the immune system is the most vulnerable and feels the changes in the environment. At the same time it was pointed out that the non-invasive method for determining the human immunity is the most accessible.