False-positive results for rapid diagnostic tests for malaria in patients with rheumatoid factor

J Clin Microbiol. 2014 Oct;52(10):3784-7. doi: 10.1128/JCM.01797-14. Epub 2014 Jul 23.


Four different rapid diagnostic tests (RDTs) for malaria were evaluated by testing 82 healthy control patients, 89 Plasmodium vivax-infected patients, and 92 rheumatoid factor (RF)-positive nonmalaria patients. The false-positive rate ranged from 2.2% to 13% in RF-positive patients. High RF levels are associated with malaria RDT false positivity.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Arthritis, Rheumatoid / complications*
  • Diagnostic Tests, Routine / methods*
  • False Positive Reactions*
  • Humans
  • Malaria, Vivax / diagnosis*
  • Rheumatoid Factor / blood*
  • Time Factors


  • Rheumatoid Factor