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Review
. 2014 Oct;42(4):169-74.
doi: 10.1249/JES.0000000000000025.

Mitochondrial plasticity with exercise training and extreme environments

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Review

Mitochondrial plasticity with exercise training and extreme environments

Robert Boushel et al. Exerc Sport Sci Rev. 2014 Oct.

Abstract

Mitochondria form a reticulum in skeletal muscle. Exercise training stimulates mitochondrial biogenesis, yet an emerging hypothesis is that training also induces qualitative regulatory changes. Substrate oxidation, oxygen affinity, and biochemical coupling efficiency may be regulated differentially with training and exposure to extreme environments. Threshold training doses inducing mitochondrial upregulation remain to be elucidated considering fitness level.

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