Variations and comparisons in medium-depth chemical peeling

J Dermatol Surg Oncol. 1989 Sep;15(9):953-63. doi: 10.1111/j.1524-4725.1989.tb03182.x.

Abstract

Two effective methods in chemical peeling, solid carbon dioxide plus trichloroacetic acid and Jessner's solution plus trichloroacetic acid, were compared clinically with photographs and histologically with serial biopsies. Carbon dioxide produced a deeper wound than Jessner's solution, and CO2 + TCA was slightly deeper than Jessner's + TCA but was probably not significantly deeper from a clinical standpoint except in correcting scarring. Triple consecutive applications of TCA can substantially increase wound depth with both combination peels.

Publication types

  • Case Reports
  • Comparative Study

MeSH terms

  • Administration, Topical
  • Adult
  • Carbon Dioxide / administration & dosage
  • Chemexfoliation / methods*
  • Drug Combinations / administration & dosage
  • Epidermis / pathology
  • Ethanol / administration & dosage
  • Facial Dermatoses / pathology
  • Facial Dermatoses / therapy
  • Female
  • Humans
  • Lactates / administration & dosage
  • Lactic Acid*
  • Necrosis
  • Pigmentation Disorders / pathology
  • Pigmentation Disorders / therapy
  • Resorcinols / administration & dosage
  • Salicylates / administration & dosage
  • Trichloroacetic Acid / administration & dosage
  • Wound Healing

Substances

  • Drug Combinations
  • Jessner's solution
  • Lactates
  • Resorcinols
  • Salicylates
  • Carbon Dioxide
  • Lactic Acid
  • Ethanol
  • Trichloroacetic Acid